@lmhayes88 you don’t 100% need a binder, but I’d recommend it. Also, just to make sure you use your meat gun before you hold it overnight, otherwise it might set up and break your meat gun.
Yes, you can use your smoker the entire way as long as it starts low enough. We’d recommend 120-125° but if your smoker will start as low as 150° then your oven probably starts that low as well so maybe not a reason to start in oven? Though, for best results, I’d still say prop a door in your smoker or oven to get an hour in at 120 (ish)°.